Development of HPLC methods for very fast trace analysis and speciation, respectively, of environmentally important pollutants (pesticides, nitrophenols, organo-mercurials etc.) in water, sediment, soil and air, also by use of monolithic columns.

      Development of HPLC methods for very fast trace analysis of substancesin biological - clinical, biotechnological and food samples.

      Development and application of HPLC methods for characterization and analysis of humic substances, air particulates and aerosol humic-like substances, as-well-as characterization of lignins, or analysis of lignins and carbohydrates in solutions origined from processes of cellulose and wood pulp bleaching, or in a waste solutions or liquors.

      Study of interactions between macromolecules and low-molecular weight substances naturally occuring in environmental samples (humic substances - pesticides) and biological samples (proteíns - pharmaceutically important substances).

      Development of HPLC methods for analysis of diastereoisomers and enantiomers of chiral pesticides (conazoles, pyrethroids) in environmental matrices.

      Research in the field of tenzides application for environmental sample pre-treatment (cloud-point extraction) and HPLC analysis (micellar liquid chromatography).